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Which tissue has the highest Tissue Weighting Factor?

  1. Skin

  2. Breast

  3. Gonads

  4. Lung

The correct answer is: Gonads

The tissue with the highest Tissue Weighting Factor is the gonads. The Tissue Weighting Factor (TWF) is a measure used in radiation protection to assess the relative risk of cancer from radiation exposure to different types of tissues. Gonadal tissues are considered to be highly radiosensitive due to their critical role in reproduction and the potential for hereditary effects. The gonads are vulnerable to radiation-induced mutations and damage, which can lead to genetic effects in future generations. Consequently, they have been assigned a higher weighting factor in order to reflect the increased sensitivity and risk associated with radiation exposure to these tissues. This understanding is essential for radiologic practice, as it emphasizes the need to minimize radiation exposure to gonadal tissues during imaging procedures whenever possible to protect both patient health and genetic material.