CAMRT Radiography Practice Exam

What is a true statement regarding the risks of intravascular contrast media with metformin?

1. It can cause renal impairment

2. It may not accumulate in renal dysfunction

3. It does not lead to lactic acidosis

4. It can result in lactic acidosis if renal dysfunction occurs

The correct answer is: It can result in lactic acidosis if renal dysfunction occurs

A true statement regarding the risks of intravascular contrast media with metformin is that it can result in lactic acidosis if renal dysfunction occurs. Metformin is primarily eliminated by the kidneys, so any impairment in renal function can lead to an accumulation of metformin in the body. When intravenous contrast media is used, especially those containing iodine, it can sometimes impair kidney function temporarily. If a patient taking metformin experiences a decline in renal function after receiving contrast, the risk of lactic acidosis increases significantly. Lactic acidosis is a serious condition characterized by an accumulation of lactic acid in the body, which can occur when metformin builds up due to reduced clearance in the case of compromised kidney function. Therefore, monitoring renal function and considering the timing of metformin administration in relation to contrast media usage is essential to prevent serious complications such as lactic acidosis. This understanding is crucial in the radiographic practice to ensure patient safety when planning imaging studies that involve contrast administration.